靶向药物实验室

简历：

教育经历：

2003.09-2007.06 沈阳药科大学，制药工程，本科

2007.09-2010.06 浙江中医药大学，药剂学，硕士

2015.06-2021.12 烟台大学，药剂学，博士

工作经历：

2010.06-2022.07 绿叶制药集团研发中心

2022.08-至今   烟台药物研究所

研究方向：

从事抗肿瘤靶向药物研究，主要方向：多肽偶联药物的研究

发表论文：

1. Ni L., Li Y. Anti-HER2 single-chain Fv fragment-decorated DM1 nanoparticles for specific targeting of HER2-positive breast tumor cells. J Biomed Nanotechnol., 2021, 17(3): 447-455.

2. Duan D. D., Wang A., Ni L., Zhang L., Yan X., Jiang Y., Mu H., Wu Z., Sun K., Li Y. Trastuzumab- and Fab′ fragment-modified curcumin PEG-PLGA nanoparticles: preparation and evaluation in vitro and in vivo. Int J Nanomedicine., 2018, 13: 1831-1840.

3. Chu L., Wang A., Ni L., Yan X., Song Y., Zhao M., Sun K., Mu H., Liu S., Wu Z., Zhang C. Nose-to-brain delivery of temozolomide-loaded PLGA nanoparticles functionalized with anti-EPHA3 for glioblastoma targeting. Drug Deliv., 2018, 25(1): 1634-1641.

4. Ma P., Zhang X., Ni L., Li J., Zhang F., Wang Z., Lian S., Sun K. Targeted delivery of polyamidoamine-paclitaxel conjugate functionalized with anti-human epidermal growth factor receptor 2 trastuzumab. Int J Nanomedicine., 2015, 10: 2173-90.